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GLP-1 receptor agonist drugs, including semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro), have been transforming obesity and type 2 diabetes treatment

Anxiety Disorders Anxiety disorders were addressed through shock probe/burying tests and light/dark paradigms, with BPC-157 showing anxiolytic effects comparable to diazepam but with a different behavioral profile

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Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation