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Phase 1 is characterized by simple steatosis and is considered harmless
Patients treated with Tirzepatide experienced a greater reduction in fat mass relative to lean mass, leading to better overall body composition
doi: 10.1093/asj/sjad211
The SURPASS-2 trial, which directly compared tirzepatide 15mg to semaglutide 1mg, found tirzepatide produced greater reductions in LDL cholesterol (11.4% vs 7.9%) and triglycerides (23.5% vs 16.2%) at 40 weeks
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Sticking to Injection Routines is Still Important If the pen sits out overnight but stays usable, keeping doses consistent is still key
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