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Description

Mechanistically it works through the Folate-AICAR-AMPK pathway, disrupting the folate-methionine cycle in a way that mirrors some effects of methotrexate, without the same toxicity profile (Wan 2023)

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One action is to interfere with tyrosinase, an enzyme that helps make melanin (skin pigment)

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This makes it particularly appealing for athletes aiming to maintain training intensity with less downtime

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