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Once reconstituted, the peptide bonds become vulnerable again to aqueous hydrolysis, and oxidation of susceptible residues (tryptophan and methionine analogs in the sequence) begins
Presented for research literature review only Tiltman AJ et al
The challenges: GLP-1s can also: Slow gastric emptying, which increases operative risks Cause slower wound healing if nutritional intake is low Lead to muscle loss, which can reduce recovery strength Continue to suppress appetite during a period where nutrition is critical Some surgeons require: A pause before surgery (often 24 weeks) Evidence of stable nutrition A personalised post-operative plan to avoid nausea and ensure adequate protein intake In short, GLP-1s can help, but they must be used mindfully and usually require a pre- and post-surgery strategy with your healthcare provider