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A late and serious manifestation of niacin deficiency is pellagra, a clinical symptom complex principally affecting the GI tract, skin, and CNS, producing symptoms of diarrhea, dermatitis, and dementia, respectively

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Supplementation with gamma-glutamylcysteine has shown to increase cellular glutathione levels above homeostasis [14] and therefore proves to have potential value as a preventative therapy for osteoporosis by reducing oxidative stress and optimizing Vitamin D and calcium absorption

When to Call a Doctor If side effects persist or worsen, reach out to your provider

( A ) and ( B ) ROS measured using the MitoSOX assay in RKO and DLD-1 cells, treated as indicated

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