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Secondly, current surgical treatments for Grades III-IV injuries frequently fail to restore native muscle architecture, highlighting the need for combinatorial approaches involving cytokine-targeted biologics, such as anti-TGF- antibodies (39) and biomaterials engineered to emulate macrophage-derived Wnt7a signaling (40)
Presented for research literature review only Hall AG et al
However, the current hypothesis is that activation of glia may act as a neuroprotective mechanism for A phagocytosis at early disease stages but become detrimental later on
While nutrition research supports the benefits of dietary intervention with key antioxidant micronutrients and phytonutrients, targeted combination therapies appear to elicit greater benefits than any one alone
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6 The Clichy criteria 66,69 can also be used
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