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Description

Allodynia appears among the top 50 adverse reactions reported for tirzepatide in the FAERS system

Limited long-term data exists on GLP-1 use specifically in autoimmune thyroid disease

Its half-life in preclinical models is roughly 2 hours, longer than sermorelin, because the D-amino acids and C-terminal amide block proteolytic degradation

The constellation of risk factor improvements provides reasonable expectation of cardiovascular benefit that formal trials may confirm