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No high-quality clinical trial has demonstrated that B12 injections produce meaningful weight loss outcomes independent of dietary and exercise changes

Important scope note: virtually all mechanistic data on BPC-157 are derived from in vitro assays or rodent (rat, mouse) injury models

The preservative in bacteriostatic water helps reduce this risk, making it a more suitable choice in these cases

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While no major safety flags have emerged from either the scientific literature or widespread anecdotal use, the absence of large-scale human data means users should proceed carefullyespecially if considering high doses or long-term use

High-fat meals are the worst offenders for nausea because fat already slows gastric emptying on its own