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Zelko et al

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Plus another reason its so potent is because of the decreased binding of Long R3 IGF-1 to all known IGF binding proteins

stimulants e.g., Dexedrine, pure dextroamphetamine sulfate, commercially available from Smith Kline and French located in the United Kingdom side effects e.g., fast wear-off of the therapeutic effect of the stimulant active ingredient causing rebound symptoms, cardiovascular stress/disorders (e.g., increased heart rate, hypertension, cardiomyopathy), other side effects (e.g., insomnia, Rebound/ Behavioral deterioration Rebound symptoms include, for example, irritability, crankiness, hyperactivity worse than in the unmedicated state, sadness, crying and in rare cases psychotic episodes

Annals of General Psychiatry, 5 , S306

AOD-9604 does not affect IGF-1 because it lacks the receptor-binding domains necessary to activate growth hormone receptors