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BAL fluid, cell lysates, or apical culture supernatants were incubated with glutathione peroxidase (Sigma-Aldrich, G6137), cumene hydroperoxide (Sigma-Aldrich, 247502), glutathione reductase (Sigma-Aldrich, G9297), and NADPH (Sigma-Aldrich, N1630) for 30 minutes at 25C
other compounds may ultimately prove safe and useful for patient care, while others are just biologically implausible
You sometimes can see this in people that take a lot of growth hormone
A disrupted redox balance, particularly elevated oxidized glutathione (GSSG), is implicated in brain aging and neurodegeneration
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