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Clinical studies of incretin receptor agonists provide evidence of cardiovascular benefit, but they do not directly demonstrate anti-fibrotic effects, as fibrosis has not been measured as a primary outcome in major trials
First, the endogenous peptide must exhibit reproducible physiological effects supported by genetic, pharmacologic, or observational evidence
This dual action of Tirzepatide can lead to more significant weight loss with potentially less side effects
However, more serious side effects are possible and can include an increased risk of low blood sugar, inflammation of the pancreas (pancreatitis), and gallbladder problems
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