Cardiovascular effects Heart rate increased in a dose-dependent manner during the first 24 weeks of treatment, with the largest average increase being approximately 6.7 beats per minute at the 12 mg dose
Med Clin 2022
list prices (2025): $900$1,300 per month without insurance $11,000$16,000 per year at retail pricing Manufacturer coupons typically expire after 612 months Coverage reality: Medicare: limited obesity coverage Medicaid: varies by state Employer plans: increasingly restrictive prior authorization Weight regain often occurs after discontinuation Projected pricing trends: Near-term (35 years): modest price erosion, not collapse Medium-term (510 years): biosimilars and next-gen entrants may reduce prices 3050% Long-term: combination therapies likely raise per-patient spend again This is not a short-course drug market
Eggs, dietary choline, and nonalcoholic fatty liver disease in the framingham heart study
Once you stop taking them, the impact on your gut microbiome may diminish. Even when we went away for a beach weekend and I forgot to bring them, I noticed I didnt get super hungry
Mild soreness at the injection site may occur temporarily