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While clinical trials have yet to be conducted on epithalon, epithalamin has been approved in Russia as a treatment of menopause-related symptoms, anovulatory infertility, and hormone-dependent tumors [2]
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However, the most critical evidence gap remains the need for large-scale, multicenter, randomized controlled trials in COPD populations
10.1080/03602532.2017.1306544 100 WangL.ShengW.TanZ.RenQ.WangR.StoikaR.et al (2021b)
Acknowledgements We thank Junko Sato and Mayumi Suda and the Biomedical Research Unit of Tohoku University Hospital for technical assistance with the experiments