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Its effects are dose-dependent and context-dependent
Many of the symptoms caused by low B12 levels are not specific to B12 deficiency, which can cause the condition to go undetected
Aromatic amino acids were provided to circumvent the inactivating effect of H 2 O 2 upon the aromatic biosynthetic pathway (Sobota et al., 2014)
Further studies showed that different subtypes of T cells had apparently different effects on microglia
Our findings do not exclude a positive role for endosomal signaling or -arrestin-1 recruitment in acute responses to physiological GLP-1, but highlight how the kinetic context must be taken into account when exploiting noncanonical pathways during drug development
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