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This heterogeneity in CV benefits across the trials, also among studies in which drugs of the same class have been used, could be explained by different study designs (i.e
Calcium oxalate crystals and oxalate induce an epithelial-to-mesenchymal transition in the proximal tubular epithelial cells: contribution to oxalate kidney injury
Time to maximum concentration (Tmax) ranges from 8 to 72 hours post-injection, with clearance of approximately 0.06 L/h
The first figure in the paper is the participant flow chart
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10.1038/nrc2228 Nat
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