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Midlife Metabolic Biology: Why Calibration Becomes Appealing GLP-1 dose calibration becomes appealing in menopause because several biological shifts occur at the same time
There is no additional benefit in wearing the patch longer than 8 hours
Effects typically develop within 12 to 72 hours
The cardiometabolic improvements seen during semaglutide treatment reverted towards the baseline in our study, similar to the findings in the STEP 1 study ( When interpreting the endocrine and cardiometabolic outcomes, it is important to highlight that participants in our cohort were already treated with metformin before the semaglutide intervention, therefore prior the baseline assessment
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