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Expert opinion Hunt et al 23 Data from randomized controlled trials and observational studies for parenteral treatment are lacking
For instance, the NICE guideline says that with total B12 values of over 350 ng/L,0 deficiency is unlikely
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Within 48 hours after injection of 100 or 1000 mcg of vitamin B12, 50 to 98% of the injected dose may appear in the urine
The cost differential can be substantial, with cyanocobalamin costing roughly one-tenth the price of methylcobalamin in pharmaceutical quantities
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Eur J Gen Pract 12
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