Farxiga/Forxiga is not currently approved for weight loss as a standalone indication in non-diabetics, but the evidence is accumulating: Currently, if weight loss is the primary goal in a non-diabetic patient, GLP-1 agonists (semaglutide/Ozempic, tirzepatide/Mounjaro) produce substantially greater weight loss (1015% vs 24%)
Orforglipron, as an oral tablet, has much simpler storage requirements
Can dark spots on the lips go away on their own
Concerning features include extensive urticaria, significant swelling beyond the injection site, intense pruritus, or rapid onset of symptoms
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NHS/SACN 25(OH)D thresholds and the 10 g autumn/winter rule and why correcting vitamin D comes first, not a peptide