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Treatment duration depends on the specific type of hyperplasia and individual patient factors
doi: 10.1007/s12257-012-0623-z 111
BRD4 degradation via CCW28-3 does not depend on RNF4 Because of the high reactivity of CCW16 required to react with two cysteines in the unstructured protein region of RNF4, we hypothesized that the RNF4-based BRD4 degrader CCW16-JQ1 (CCW28-3) may not degrade BRD4 via an RNF4 dependent mechanism 36
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