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Tirzepatide slows gastric emptying, which raises the risk of acid reflux, especially overnight when you're lying flat

Yang, X., Lin, G., Han, Z

Diabetes, Obesity and Metabolism 2003 5:6 (424-431) 49

Additional weight loss of 5-15% of current body weight has been reported in these studies, though results vary considerably and most studies have limited follow-up duration

This trend was only partially shared by other cell types like cardiac fibroblasts, which did not display the same enrichment in TCA or glycolysis pathways ( Figure 3C )

Some foodsparticularly those rich in protein and fiber may support the body's natural GLP-1 response after eating