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Short-Term GLP-1 Side Effects You May Experience Short-term side effects usually appear during the first few days or weeks of treatment

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While B12 plays a role in cellular energy metabolism, supplementing B12 in a patient who is not deficient does not increase metabolic rate or cause fat loss

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That caloric reduction means less energy available for training, less glycogen stored in muscles, and fewer raw materials (amino acids, micronutrients) available for post-workout repair