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If switching the route of administration and dosage don't help, you may also have like a substrate issue

Decreased ratios of product to precursor suggested a shift favorable to the Xant production resulting in decreased UA levels in the FENNS ( Figure 2 )

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Helps heal the tissues: Could accelerate the healing of the lining of the gut, skin, muscles, tendons, ligaments, and joints

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313,314 In one study, OA was induced in rats by injecting MIA into the knee joint, mimicking the pathological changes of human OA