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Following treatment, body weight was measured and blood obtained, before euthanasia and extraction of liver tissue for metabolomic analysis

Phase 2 trial (NEJM 2023) randomized 338 adults with obesity to retatrutide doses from 1 mg to 12 mg/week

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By progressively increasing the intensity, the protocol captured critical data on anaerobic and aerobic performance, offering insights into how supplementation influences metabolic efficiency and endurance

When he takes it: He usually takes 2 capsules before or after his largest meal of the day, often dinner or any meal containing around 50 grams or more of carbohydrates, including desserts or alcohol