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Announced by Novo Nordisk on January 17, 2025, the randomized, double-blinded, parallel-group, placebo-controlled STEP UP trial evaluated the efficacy of semaglutide 7.2 mg to semaglutide 2.4 mg (Wegovy) and placebo in more than 1400 adults with obesity and without type 2 diabetes (T2D)

Correspondingly, this implies that the cardiac benefits of GLP-1 agonism may arise in part from this metabolic support

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After 6 months of therapy, muscle strength in the bench press responsive muscles did not increase in both groups and showed a statistically significant increase in the leg press responsive muscles in the GH group. Weight Loss Ipamorelin and Sermorelin are also great peptides for weight loss

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