Who should not take GLP-1 drugs if they have stomach issues
53 With respect to cardiac remodeling, left ventricular cardiomegaly and interstitial fibrosis was countered in mouse models of inactivated GIPR, 54 and deleterious effects of GIP were reported in myocardial infarction
The SELECT trial demonstrated that semaglutide reduced major adverse cardiovascular events (heart attack, stroke, cardiovascular death) by 20 percent in overweight and obese adults with established cardiovascular disease
Certain RA medications can affect gastrointestinal functionmethotrexate may cause nausea, and some biologics alter gut permeability
Some telehealth providers, like Henry Meds, are still advertising and selling compounded tirzepatide
Long-term efficacy, safety & duration: While GLP-1s have shown impressive short-term results, the long-term picture remains blurry