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A significant negative latitude-dependent relationship was detected for carriage of the T allele, with occurrence of the cSHMT-C1420T polymorphic allele decreasing with increase in latitude ( r 2 =0.73, p 3R frequency in reported African and Eurasia studies found a significant negative relationship between latitude and frequency of the 3R allele ( r 2 =0.12, p =0.039) (Fig
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This substrate availability problem explains why BCAAs alone stimulate muscle protein synthesis approximately 22% above placebo but remain roughly 50% less effective than whey protein containing similar BCAA amounts
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Here are more details on the potential side effects of MT1 [19]: Long-term phase 3 studies of up to 8 months in duration highlight a favorable safety profile for MT1 without noting any significant adverse effects, even after 180-270 days of administration
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