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While peptides like growth hormonereleasing peptides (GHRPs), kisspeptin, and some antioxidant peptides have shown early promise in small studies, the data is mixed and there are few larger human trials

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Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

Participants were allocated in a 21:3:3:7 ratio to weekly injections of one of four regimens: fixed-dose cagrilintide 2.4 mg plus semaglutide 2.4 mg, semaglutide alone, cagrilintide alone, or placebo

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Regulatory status: investigational and research-only DSIP is not FDA-approved as a drug