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Arguments Against the FDAs Decision: Potential Health Benefits: Advocates emphasize the reported benefits observed in animal studies and limited human use, arguing these should be weighed alongside regulatory concerns
Antioxidant and anti-inflammatory activity GHK-Cu has been studied for its ability to reduce oxidative damage markers, modulate inflammatory cytokine expression (particularly IL-6 and TNF-), and support cellular resilience under stress conditions
As a tetrapeptide, Epithalon is linked with telomere elongation, which could contribute to cellular lifespan extension
Note that, in other experiments, the same method was used to determine cagrilintide purity
The discovery that GHK-Cu binds directly to SIRT1 (Li et al., 2025) has generated particular interest, as SIRT1 is a central regulator of cellular longevity and stress resistance
GHK-Cu is a tripeptide-copper complex: Gly-His-Lys coordinated to copper(II) ion
