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Synergistic anti-leukemic activity with combination of FLT3 inhibitor quizartinib and MDM2 inhibitor milademetan in FLT3-ITD mutant/p53 wild-type acute myeloid leukemia models

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(1,2) BPC157 is a synthetic peptide that has been investigated for its effects on vascular endothelial growth factor (VEGF) signaling, nitric oxide (NO) pathways, and fibroblast activity