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doi:10.1097/01.ju.0000112918.74410.94
Pivotal Phase 3 trials Trial SURMOUNT-1 (NEJM 2022) Population 2,539 adults, obesity, no diabetes
These secondary messengers are hypothesized to increase calcium release from intracellular stores and activate protein kinase C (PKC), together contributing to vesicular secretion from somatotroph cells
When you do it this way, you have time to adjust so you wean off the medications
J Hepatol 2024
In view of the recent interest in GLP-1R agonism as a nonalcoholic fatty liver disease treatment, we evaluated liver histology after chronic treatment, showing greater steatosis resolution with exendin-phe1 (Fig
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