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Randomized participants initiate treatment with 3 mg OD oral semaglutide or placebo from weeks 04 and follow a 4-week dose-escalation regimen to 7 mg during weeks 48, after which a treatment dose of 14 mg is reached
Hypoglycaemia risk increases when GLP-1 medications are combined with insulin or sulfonylureas, with sweating being a classic warning sign requiring blood glucose monitoring
That is especially useful if your care goals include more than weight loss alone
If week 4 symptoms remain severe, extending the 5mg phase to three weeks rather than two represents sensible adaptation, not failure
Best practices ensure high-quality results and compliance
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