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All the patients underwent clinical assessment, anthropometric measurement, oral glucose tolerance test (OGTT) and laboratory assays
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Long-term safety data are sparse, and tolerability issues, particularly gastrointestinal side effects, often interfere with adherence
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[4] [5] The standard of care remains disease-modifying antirheumatic drugs (DMARDs), including conventional synthetic DMARDs like methotrexate as first-line therapy, with escalation to biological DMARDs or targeted synthetic DMARDs if disease activity remains inadequately controlled, following a treat-to-target approach
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