tirzepatide e semaglutide EASD 2023: meta-analysis shows superiority to Semaglutide vs. Tirzepatide: Which GLP-1

this effect may counteract the cardiovascular complications by the reduction of the systemic inflammation ( Figure 1 3.2 GLP1-RAs and AMPK GLP-1 (Glucagon-like peptide 1) is an incretin hormone, secreted from L-cells of the small intestine in a glucose-dependent manner, that enables stimulation of insulin secretion, increases pancreatic -cell mass, and inhibits glucagon secretion and gastric emptying, thereby reducing postprandial glycemia

The dual agonists targeting GLP-1 and another receptor (GIP) do not retard gastric emptying, based on reports to date

Each escalation raised the stakes

Scan for full doses, not fairy dust

Understanding how it compares to similar peptides helps contextualize its use

Wright N, Wilson L, Smith M, Duncan B, McHugh P