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Key points include: use an alcohol swab on the vial stopper before each draw, inject bacteriostatic water slowly down the side of the vial (never directly onto the powder), and gently swirl rather than shake to dissolve

A novel class of incretin-based therapies consisting of glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) and dual (GLP1/glucose-dependent insulinotropic polypeptide [GIP]) RAs acts by lowering blood sugar and inducing weight loss

Other GLP-1 agonists include dulaglutide (Trulicity), liraglutide (Saxenda and Victoza), exenatide (Bydueron and Byetta), semaglutide (Rybelsus), and tirzepatide (Mounjaro)

68 Of note, the BNIP3/NIX pathway was specifically up-regulated when mitochondrial oxidative stress was generated in the hypoxic environment to further induce mitophagy

In adults, IGF-1 and its analogues have been shown to reduce neuronal death and protect neurons against insults like stroke, Alzheimers disease, Parkinsons disease, and more