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The PIONEER 1-8 clinical studies show that 1.7 to 12% of patients discontinued Rybelsus treatment due to side effects, with gastrointestinal side effects being the most common

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To assess whether the NF-B pathway plays a crucial role in EAAT3 expression in an in vivo setting, we generated Gprc5a-ko/SPC-dnIB- mice by crossbreeding Gprc5a -ko mice with SPC-dnIB- mice

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