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10.1094/MPMI-4-014 42 EdwardsR.DixonD

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Carbon dots, thanks to their abilities to penetrate the BBB and the excellent photoluminescence may represent promising nanocarriers for drug delivery in neural compartments and for potential use as AD therapy, by inhibiting oxidative stress, neurotoxicity as well as for restoring nerve damage and maintaining neuronal morphology according to the released payload (Kuang et al., 2020

In animals, specifically DR in its various forms (CR/IF/STS, KD, protein restriction) has shown a potential for simultaneously targeting many of the pathways associated with insulin and IGF signaling, usually with no serious, or with even beneficial side effects such as a differential stress response between normal and tumor tissue

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