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Metabolic adaptation is the most common cause of plateaus, occurring when the bodys metabolic rate decreases in response to weight loss
Same one-week washout principle applies
Those are the same effects that make GLP-1 receptor agonist medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) so effective for blood sugar and weight management
References 1 UmpierrezGEDavisGMElSayedNAFadiniGPGalindoRJHirschIBet al
A metanalysis by Bray et al
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