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A sensitivity analysis accounting for factors such as demographics, starting BMI classification, residence in a socially vulnerable area, comorbidities, and baseline HbA1c level also found that patients on GLP-1s were more likely to experience weight loss and to reduce their HbA1c levels

Two of the most popular drugs are semaglutide , the active ingredient in Wegovy and Ozempic, and tirzepatide , the active ingredient in Mounjaro

39 It was approved by the US FDA in 2014 to treat obesity (Saxenda , Novo Nordisk, Plainsboro, NJ, USA), after first being approved as a type 2 diabetes medication (Victoza , Novo Nordisk) in 2010 (Table 1)

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PMID: 10561358