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Zygote 2020;29(1):1-11

Symptoms and outcomes can include: Recurrent miscarriage Difficulty conceiving Neural tube defects (spina bifida, cleft lip/palate) Down syndrome Preeclampsia and pregnancy hypertension If youre planning pregnancy, supporting methylation and folate pathways is critical

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Sears, M

Although the anxiety and depression symptom instruments that were used have been validated, they are self-report questionnaires and only evaluated symptom severity, and they do not necessarily have diagnostic value