Chronic conditions with poor blood supply -- where the tissue needs ongoing support to rebuild vasculature -- fit this profile well
Nitric oxide mediated inhibition of antigen presentation from DCs to CD4 + T cells in cancer and measurement of STAT1 nitration
10.1179/135100009X466131 31 GaoH
Changes in the transcription of iron-regulatory genes such as IREB2 , FBXL5 , TFRC , FTH1 , and FTL affect the sensitivity to erastin-induced ferroptosis, with this sensitivity positively correlating with intracellular iron abundance ( Figure 3
The driver may be systemic or involve a different pathway, including mast-cell activation
de Groot et al., Reference de Groot, Smeets, Rowson, Bulsing, Blonk, Wilkinson and Semin2015b