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Moreover, Met contributes to several biological processes, such as protein synthesis, epigenetic regulation, nuclear function, cellular redox potential, phospholipid homeostasis, among others
eBioMedicine 82:104191
When systemic glutathione levels are low, the resulting unchecked oxidative stress acts as a constant irritant to mast cells, keeping them in a hyper-reactive state
Acknowledgements The authors work was supported by the National Science and Technology Council, Taiwan (NSTC 113-2314-B-038-084 and NSTC 113-2314-B-039-044)
This presents a meaningful clinical concern, particularly in populations exposed to polypharmacy or managing complex comorbidities
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