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In general, watch for any sustained change in vision, VanderBeek says

In a randomized controlled trial, Falutz et al., New England Journal of Medicine (2010) found that Tesamorelin significantly reduced VAT in HIV-infected patients with abdominal fat accumulation, leading to a healthier body composition and reduced cardiometabolic risk

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This synthetic compound was shown to increase muscle mass by 2.5 times in animal studies, though it has never been studied in humans

The tirzepatide to semaglutide switching guide provides relevant context for the GLP-1 component transition