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Storage duration critically impacts effectiveness - reconstituted GHK-Cu lasts only 21-28 days refrigerated due to copper oxidation concerns (shorter than most peptides), requiring strategic reconstitution of amounts usable within this window rather than preparing entire vials at once

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Pregnant and nursing individuals lack sufficient safety data and should not supplement without explicit provider approval

These disorders include Alzheimers disease (AD), Parkinsons disease, amyotrophic lateral sclerosis (ALS), and Huntingtons disease

Injecting in the same spot repeatedly

In addition, BPC 157 reduces severe encephalopathies (NSAID overdose, Lojo et al., 2016