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The surrounding muscle will absorb the medication right away
Very high doses of B12 taken orally may occasionally cause mild gastrointestinal disturbance in some individuals, though this is uncommon
The opposite is also possible
Medications such as metformin or proton pump inhibitors can significantly hinder B12 absorption
The guideline explicitly states: "Clinicians should screen for depression, anxiety, and disordered eating behaviors before initiating and during pharmacotherapy for obesity in adolescents" [19]
The appropriate choice depends on individual health goals, risk factors, contraindications, and preferences regarding the balance between potential benefits and side effect profiles
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