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Effects on body weight Another extremely interesting aspect of the mode of action of GLP-1 and GIP mimetics is their effect on certain processes involved in appetite control (Figure 3)

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Taken together, these data establish that a mixture of -synuclein containing both monomeric and high molecular weight conformers of this protein significantly augments the expression, production and release of classical proinflammatory molecules from BV2 cells, while -synuclein misfolded in the presence of dopamine (SYN DA ) causes a dampened response, despite the presence of high molecular weight -synuclein species suggesting that the structure of -synuclein modified by dopamine is different than -synuclein modified in the absence of this neurotransmitter

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