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The AR belongs to Subfamily 3 of the Class 1 Nuclear Receptor Superfamily, comprising of steroid receptors which regulate key metabolic processes under a highly conserved DBD, all undergoing homodimerization upon nuclear translocation (Class I: progesterone receptor (PR), glucocorticoid receptor (GR), mineralocorticoid receptor (MR), and Class II: estrogen receptor (ER) alpha and beta) [22, 23]

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