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Sex was not considered as a biological variable in the primary study design because (i) cyclical hormonal variation in female mice is a known confounder of LPS-induced inflammatory cytokine responses, and (ii) the C57BL/6J LPS doseresponse and time course on which our paradigm was based has been characterized primarily in males in prior literature
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No, semaglutide does not appear on standard employment drug screening panels, which test for substances of abuse like opioids, amphetamines, and cannabinoids
