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Probably due to the lack of complementary interacting residues, superimposing GIP or GLP-1 to GCG bound to GCGR shows that the aligned peptides reduced favorable contacts with GCGR compared to GCG by removing one hydrogen bond (Y10 P (GCG)/Y10 P (GIP)/V16 P (GLP-1)-Q142 1.40b (GCGR)) and pi-pi stacking (Y13 P (GCG)/A13 P (GIP)/Y19 P (GLP-1)-Y138 1.36b (GCGR)) and by repulsing the interaction between Y1 P (GIP) and I235 3.40b (GCGR)
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PiaggiSMarchiECarnicelliVZucchiRGrieseMHectorAet alAirways glutathione S-transferase omega-1 and its A140D polymorphism are associated with severity of inflammation and respiratory dysfunction in cystic fibrosis
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What are historical, present, and forecasted market shares and growth rates of various segments and sub-segments of the obesity drugs market
& Sreejayan, N
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