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DHA not only reduces GSH to GSSG but also inactivates GPX4 directly, facilitating LPO accumulation and cell ferroptosis collaboratively (Figure 5E)

For example, ACE inhibtors carry a risk of harm if used during pregnancy as a boxed warning

When you cut calories and drop pounds, some muscle loss is almost inevitable

This typically equals around 15% of their body weight when combined with a reduced-calorie diet and regular exercise

Appetite suppression becomes well-established, and healthier eating patterns are reinforced

This dual mechanism distinguishes it from other incretin-based therapies that target only the GLP-1 receptor