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However, anti-fibrotic actions of FGF19 signaling do not appear to depend on FGFR4 signaling, based on three lines of evidence
These receptors include retinoic acid-related orphan receptor (ROR), REV-ERB, and peroxisome proliferator-activated receptor (PPAR) (Yin et al., 2007
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The defining structural feature is a side-chaintoside-chain lactam between the -carboxyl of Asp(2) and the -amine of Lys(7), producing a homodetic isopeptide macrocycle
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